Today, a paper appeared in Nature describing the full genome sequence of Jim Watson. This is the first human genome sequence that has been published using next-generation sequencing technology - 454 in this case. Press releases have been issued by Illumina and ABI announcing the completion of a full human genome sequence, but this is the first peer reviewed paper.
Cell has published a review article summarizing the state-of-the-art next generation sequencing technologies and their capabilities. This article focuses on the 454, Solexa and SOLiD platforms.
Nature Genetics has published a nice article summarizing the sequencing technologies on the horizon.
February 11, 2008 11:36 AM
George Church has recently released his version of a next-generation sequencer.
February 11, 2008 10:58 AM
This weekend, there was a flurry of excitement over the announcement of a new sequencing technology that could eclipse the Solexa/454/SOLiD technologies as far as time, read length, and throughput goes.
Here is a link to the Pacific Biosciences website.
And a story about this technology from the New York TImes
January 30, 2008 12:42 PM
An interesting story was published recently in Wired magazine describing the new consumer market of personal genomics. The ramifications of this on our culture will be profound, and are only the tip of the iceberg.
January 28, 2008 10:40 AM
A study published online in Science describes the use of 454 sequencing to identify a new polyoma virus that causes merkel cell carcinoma.
January 28, 2008 10:29 AM
Plans have recently been announced to sequence the genomes of 1,000 humans over the course of the next three years.
Click
here to read the full story,